Medizinische Grundlagenforschung
Preisträger Medizinische Grundlagenforschung 1988 – 2019
| 2019 | Dr. Luise Erpenbeck | Chromatin swelling drives neutrophil extracellular trap release. |
| 2018 | Dr. Sebastian Theurich | IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis. |
| 2017 | Prof. Dr. Oliver Söhnlein | Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment. |
| 2016 | Dr. Markus Landthaler | A Variety of Dicer Substrates in Human and C. elegans. RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway. |
| 2015 | Dr. Andrew Pospisilik | Paternal diet defines offspring chromatin state and intergenerational obesity. Heme Oxygenase-1 Drives Metaflammatoin and Insulin Resistance in Mouse and Man. |
| Dr. Simon Fillatreau | IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. | |
| 2014 | Dr. Andrea Ablasser | Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. |
| 2013 | Dr. Marisa Karow | Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells. |
| 2012 | Prof. Dr. H. C. Reinhardt | DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization. |
| 2011 | Dr. Daniel N. Wilson | Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition. Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. |
| 2010 | Prof. Dr. Veit Hornung | RIG-I-dependent sensing of poly (dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. |
| 2009 | Prof. Dr. Norbert Hübner | Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. |
| 2008 | Prof. Dr. Bernhard Nieswandt | An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice. Loss of talin1 in platelets abrogates integrin activation, platelet aggregation and thrombus formation in vitro and in vivo. |
| 2007 | PD Dr. Volker Heussler | Manipulation of Host Hepatocytes by the Malaria parasite for Delivery into Liver Sinusoids. |
| 2006 | Dr. Ann-Kristin Müller | Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. |
| Prof. Dr. Ivan Dikic | Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Ubiquitin-binding domains in Y-family polymerases regulate translesion Synthesis. | |
| 2005 | PD Dr. med. Karl Rudolph | Telomere length is reset during early mammalian embryogenesis. Mitogen Stimulation Cooperates with Telomere Shortening To Activate DNA Damage Responses and Senescene Signaling. |
| 2004 | Dr. Michael Zeisberg | BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. |
| Dr. Kirsten Lauber | Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal. | |
| 2003 | Prof. Dr. Christian Weber | Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury. JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes. |
| 2002 | Prof. Dr. Patrick Cramer | Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution. |
| 2001 | PD Dr. Elke Roeb | An MMP-9 mutant without gelatinolytic activity as a novel TIMP-1-antagonist. |
| 2000 | Dr. habil. Thomas Willnow | An Endocytic Pathway for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3. |
| 1999 | Prof. Dr. Richard Kroczek | CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. |
| PD Dr. Rita Gerardy-Schahn | Die Bedeutung der Polysialinsäure für das Wachstum und Metastasierungsverhalten neuroendokriner und lymphoider Tumoren. | |
| PD Dr. Ortrud Steinlein | A Potassium Channel Mutation in Neonatal Human Epilepsy. | |
| 1998 | Dr. Stefan Offermanns | Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα13 Deficiency. |
| 1997 | Prof. Dr. Dr. Manfred W. Kiliman | Mutations in the testis/liver isoform of the phosphoylase kinase γ subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans. |
| 1996 | Prof. Dr. Dietmar Vestweber | The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor. |
| 1995 | Dr. Ludwig Thierfelder | A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2. |
| 1994 | Prof. Dr. Martin Krönke | Human 55-kDa receptor for tumor necrosis factor couples to signal transduction cascades. |
| 1993 | PD Dr. Peter Gierschik | sozyme-selective stimulation of phospholipase C-β2 by G-protein βγ-subunits. |
| 1992 | PD Dr. Klaus Ley | Endothelial, not hemodynamic differences are responsible for preferential leukocyte rolling in rat mesenteric venules. |
| 1991 | Prof. Dr. Stefan H. E. Kaufmann | T-Cells against a bacterial heat shock protein recognize stressed macrophages. |
| 1990 | Prof. Dr. Bernhard Fleischer | Stimulation von T-Lymphozyten durch mikrobielle Exotoxine: Ein in der Evolution konservierter Mechanismus. |
| 1989 | Prof. Dr. Peter C. Weber PD Dr. Sven Fischer Dr. Clemens von Schacky |
zelluläre Funktionen. |
| 1988 | Prof. Dr. Wolfram H. Gerlich Dr. Klaus-Hinrich Heermann |
Wege zu einem optimalen Impfstoff gegen Hepatitis-B-Viren. |
| Prof. Dr. Karl-G. Dorst | Entwicklung und Erprobung eines integrativen Behandlungsprogramms bei essentieller Hypertonie. | |
Frühere Preisträger
Die Wissenschafts- und Publizistikpreise der GSK-Stiftung werden bereits seit Ende der achtziger Jahre verliehen. Zu den Preisträgern gehören Wissenschaftler und Mediziner, die für hervorragende wissenschaftliche Arbeiten in der medizinischen Grundlagenforschung und der Klinischen Forschung geehrt werden. Die Publizistikpreise gingen an Journalisten aus den Bereichen Print, Hörfunk und Fernsehen, die es verstanden haben, auch schwierigste Sachverhalte klar und verständlich auf den Punkt zu bringen.
Hier eine Übersicht früherer Preisträger: