Klinische Forschung
Preisträger Klinische Forschung 1989 – 2016
2016 | Dr. Dr. Marc Aurel Busche | Rescue of long-range circuit dysfunction in Alzheimer’s disease models. Decreased amyloid-ß and increased neuronal hyperactivity by immunotherapy in Alzheimer’s models. |
2015 | Der Preis für klinische Forschung wurde 2015 nicht verliehen | |
2014 | Prof. Dr. Roman Thomas | Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. A Genomics-Based Classification of Human Lung Tumors. |
2013 | Dr. Manuel Friese | TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. |
2012 | Dr. Jürgen Schauber | Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions. |
2011 | Prof. Dr. Eicke Latz | NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. |
2010 | Prof. Dr. Stefanie Dimmeler Dr. Angelika Bonauer |
MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice. |
2009 | PD Dr. Reinhard Voll | Induction of inflammatory and immune responses by HMGB1-nucleosome complexes – implications for the immunopathogenesis of SLE. The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis |
2008 | Prof. Dr. Frank Kirchhoff Dr. Jan Münch |
Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection. |
2007 | Prof. Dr. Christoph Klein | Deficiency of HAX1 causes autosomal recessive severe congenital neutropenia (Kostmann disease) – A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. |
PD Dr. Bruno Scheller | Behandlung der Restenose durch Kurzzeitapplikation von Paclitaxel: von der Zellkultur zum beschichteten Ballonkatheter. | |
2006 | Dr. Stephan E. L. Lehnart Dr. Xander H. T. Wehrens |
Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias. |
2005 | PD Dr. Ulrich E. Schaible | Saposin C is required for lipid presentation by human CD1b. Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells. |
2004 | Dr. Max S. Topp | Restoration of CD28 Expression in CD28- CD8+ Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production. |
PD Dr. Stefan Kubicka | Involvement of TRAIL and its receptors in viral hepatitis. Caspase 8 small interfering RNA prevents acute liver failure in mice. | |
2003 | Prof. Dr. Wolf-Henning Boehncke | Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model. Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation. |
PD Dr. Michael P. Schön Dr. Margarete Schön |
Tumor-selective induction of apoptosis by the small-molecule immune response modifier imiquimod. | |
2002 | PD Dr. Steffen Stenger | Induction of Direct Antimicrobial Activity Through Mammalian Toll-Like Receptors. T-cell release of granulysin contributes to host defense in leprosy. |
Dr. Stephan Ludwig Dr. Stephan Pleschka |
Influenza Virus-induced AP-1-dependent Gene Expression Requires Activation of the JNK Signaling Pathway. Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade. | |
2001 | Dr. Young-Ae Lee | A major susceptibility locus for atopic dermatitis maps to chromosome 3q21. |
2000 | Dr. Christian Körner | Carbohydrate deficient glycoprotein syndrome type IV. |
1999 | siehe Medizinische Grundlagenforschung | |
1998 | PD Dr. Michael Hallek | Molekulare Pathogenese der chronischen myeloischen Leukämie. |
1997 | Prof. Dr. Klaus-Michael Debatin | Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug induced apoptosis in leukemia cells. |
1996 | Prof. Dr. Herta Flor | Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. |
1995 | Prof. Dr. Ulrich Walter | cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. |
1994 | nicht verliehen | |
1993 | PD Dr. Erik C. Böttger | Disseminated mycobacterium genavense infection in patients with AIDS. |
1992 | Prod. Dr. Erland Erdmann Dr. Michael Böhm Dr. Robert H.G. Schwinger |
Die Herzinsuffizienz des Menschen als Regulationsstörung der Kontraktionskraft durch Veränderung der cAMP-Bildung und der Calciumhomöostase. |
1991 | Prof. Dr. Reinhard Kandolf | A search for the enteroviral capsid protein VP 1 in pancreases of patients with Type 1 (insulin-dependent) diabetes and pancreases of hearts of infants who died of coxsackieviral myocarditis. |
1990 | Prof. Dr. Michael P. Manns | Die LKM-Antikörper-positive chronisch aktive Hepatitis- eine Autoimmunkrankheit mit Modellcharakter. |
1989 | Prof. Dr. Walter Brendel Dr. Michael Delius Dr. Joseph Holl Prof. Dr. Gustav Paumgartner Dr. Michael Sackmann Prof. Dr. Tilman Sauerbruch |
Einführung der extrakorporalen Stoßwellenlithotripsie (ESWL) in die Gastroenterologie. |