Klinische Forschung

Preisträger Klinische Forschung 1989 – 2016

 
 

2016	Dr. Dr. Marc Aurel Busche	Rescue of long-range circuit dysfunction in Alzheimer’s disease models. Decreased amyloid-ß and increased neuronal hyperactivity by immunotherapy in Alzheimer’s models.
2015	Der Preis für klinische Forschung wurde 2015 nicht verliehen
2014	Prof. Dr. Roman Thomas	Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. A Genomics-Based Classification of Human Lung Tumors.
2013	Dr. Manuel Friese	TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.
2012	Dr. Jürgen Schauber	Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions.
2011	Prof. Dr. Eicke Latz	NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
2010	Prof. Dr. Stefanie Dimmeler Dr. Angelika Bonauer	MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice.
2009	PD Dr. Reinhard Voll	Induction of inflammatory and immune responses by HMGB1-nucleosome complexes – implications for the immunopathogenesis of SLE. The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis
2008	Prof. Dr. Frank Kirchhoff Dr. Jan Münch	Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection.
2007	Prof. Dr. Christoph Klein	Deficiency of HAX1 causes autosomal recessive severe congenital neutropenia (Kostmann disease) – A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.
	PD Dr. Bruno Scheller	Behandlung der Restenose durch Kurzzeitapplikation von Paclitaxel: von der Zellkultur zum beschichteten Ballonkatheter.
2006	Dr. Stephan E. L. Lehnart Dr. Xander H. T. Wehrens	Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias.
2005	PD Dr. Ulrich E. Schaible	Saposin C is required for lipid presentation by human CD1b. Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells.
2004	Dr. Max S. Topp	Restoration of CD28 Expression in CD28- CD8+ Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production.
	PD Dr. Stefan Kubicka	Involvement of TRAIL and its receptors in viral hepatitis. Caspase 8 small interfering RNA prevents acute liver failure in mice.
2003	Prof. Dr. Wolf-Henning Boehncke	Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model. Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation.
	PD Dr. Michael P. Schön Dr. Margarete Schön	Tumor-selective induction of apoptosis by the small-molecule immune response modifier imiquimod.
2002	PD Dr. Steffen Stenger	Induction of Direct Antimicrobial Activity Through Mammalian Toll-Like Receptors. T-cell release of granulysin contributes to host defense in leprosy.
	Dr. Stephan Ludwig Dr. Stephan Pleschka	Influenza Virus-induced AP-1-dependent Gene Expression Requires Activation of the JNK Signaling Pathway. Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade.
2001	Dr. Young-Ae Lee	A major susceptibility locus for atopic dermatitis maps to chromosome 3q21.
2000	Dr. Christian Körner	Carbohydrate deficient glycoprotein syndrome type IV.
1999	siehe Medizinische Grundlagenforschung
1998	PD Dr. Michael Hallek	Molekulare Pathogenese der chronischen myeloischen Leukämie.
1997	Prof. Dr. Klaus-Michael Debatin	Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug induced apoptosis in leukemia cells.
1996	Prof. Dr. Herta Flor	Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation.
1995	Prof. Dr. Ulrich Walter	cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets.
1994	nicht verliehen
1993	PD Dr. Erik C. Böttger	Disseminated mycobacterium genavense infection in patients with AIDS.
1992	Prod. Dr. Erland Erdmann Dr. Michael Böhm Dr. Robert H.G. Schwinger	Die Herzinsuffizienz des Menschen als Regulationsstörung der Kontraktionskraft durch Veränderung der cAMP-Bildung und der Calciumhomöostase.
1991	Prof. Dr. Reinhard Kandolf	A search for the enteroviral capsid protein VP 1 in pancreases of patients with Type 1 (insulin-dependent) diabetes and pancreases of hearts of infants who died of coxsackieviral myocarditis.
1990	Prof. Dr. Michael P. Manns	Die LKM-Antikörper-positive chronisch aktive Hepatitis- eine Autoimmunkrankheit mit Modellcharakter.
1989	Prof. Dr. Walter Brendel Dr. Michael Delius Dr. Joseph Holl Prof. Dr. Gustav Paumgartner Dr. Michael Sackmann Prof. Dr. Tilman Sauerbruch	Einführung der extrakorporalen Stoßwellenlithotripsie (ESWL) in die Gastroenterologie.